Controlled commissural alignment of TAVI can be achieved by planning a patient-specific orientation of the prosthesis before crimping and advancing the delivery system within the vascular anatomy in the recommended orientation.
You can submit your own anonymized CT scans for offline analysis.
The TAVI commissure alignment method has been validated in a three stage research project
Centerline of the aorta, from the descending aorta to the aortic root and left is calculated from CT-derived aortic biomodels. Assuming no torsion of the delivery catheter, the TAVI is advanced virtually through the aorta with rotational orientation perpendicular to the centerline curve of the aorta
Real TAVI valves were implanted in ten CT-derived hollowed 3D printed-phantoms obtained from aortic biomodels. CT-scans of the 3D-printed models were obtained for in silico versus in vitro comparison of both, conventional and ACA oriented implants.
19 consecutive patients with aortic stenosis accepted for TAVI have been implanted with the ACA methodology. 5 different TAVI valves from different providers have been employed. Average radial deviation from optimal target angle is less than 8º
A multicenter registry to evaluate mid-term improvement in clinical parameters soon to be started.